RT Journal Article
SR Electronic
T1 Comparison of liquid and dried sodium citrate as the anticoagulant for Thrombotest and prothrombin time estimations.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 902
OP 905
DO 10.1136/jcp.34.8.902
VO 34
IS 8
A1 Hoctor, D
A1 Bottomley, J
A1 Hyde, K
A1 Gowenlock, A H
A1 Maciver, J E
YR 1981
UL http://jcp.bmj.com/content/34/8/902.abstract
AB Samples which are taken for the Quick one-stage prothrombin time estimation for the control of patients receiving oral anticoagulant treatment are by convention taken into liquid sodium citrate anticoagulant. Dried sodium citrate has been rejected on the grounds that excessive haemolysis causes activation of clotting factors and therefore falsely short clotting times. Tests were performed with both liquid and dried sodium citrate as an anticoagulant for prothrombin time and Thrombotest. No clinically significant difference between the values given by the two anticoagulants was observed.