RT Journal Article SR Electronic T1 Combined light and electron microscope in routine histopathology. JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 425 OP 429 DO 10.1136/jcp.35.4.425 VO 35 IS 4 A1 S Jones A1 S K Chapman A1 P R Crocker A1 G Carson A1 D A Levison YR 1982 UL http://jcp.bmj.com/content/35/4/425.abstract AB We report our experience with a prototype combined light and electron microscope (the LEM 2000) with particular reference to its application to routine surgical histopathology. We found its major advantages over conventional transmission electron microscopies were due to the large grid size (7 mm diameter), low magnification capacity (x 250), and the built-in microprocessor for recording areas of interest. These features combine to reduce sampling errors and greatly facilitate orientation and relocation of fields of diagnostic importance.