@article {Hodgkinson807, author = {A Hodgkinson and T Thompson}, title = {Measurement of the fasting urinary hydroxyproline: creatinine ratio in normal adults and its variation with age and sex.}, volume = {35}, number = {8}, pages = {807--811}, year = {1982}, doi = {10.1136/jcp.35.8.807}, publisher = {BMJ Publishing Group}, abstract = {Conditions for the determination of the fasting urinary hydroxyproline: creatinine ratio (OHPr: Cr ratio) have been examined, using a resin-catalysed hydrolysis and automated colorimetric procedure for the determination of hydroxyproline. Feeding experiments with gelatin showed that hydroxyproline is rapidly absorbed and excreted in the urine and that a 12-hour (overnight) fast is sufficient to ensure correct and reproducible fasting OHPr: Cr ratios. The mean fasting OHPr: Cr ratio decreased slightly with increasing age in both men and premenopausal women but there was no significant difference between the sexes. There was, however, a significant increase in the mean ratio in postmenopausal women. The normal range of fasting OHPr: Cr ratios for men and premenopausal women was found to be 0.003--0.015.}, issn = {0021-9746}, URL = {https://jcp.bmj.com/content/35/8/807}, eprint = {https://jcp.bmj.com/content/35/8/807.full.pdf}, journal = {Journal of Clinical Pathology} }