RT Journal Article SR Electronic T1 Counterimmunoelectrophoresis in the serodiagnosis of Legionnaires' disease. JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 466 OP 470 DO 10.1136/jcp.36.4.466 VO 36 IS 4 A1 M Holliday YR 1983 UL http://jcp.bmj.com/content/36/4/466.abstract AB Counterimmunoelectrophoresis (CIE) was found to be a rapid, specific method for detecting circulating antibodies to Legionella pneumophila, using a simple ultrasonically disrupted antigen. The diagnostic specificity of the technique was 93% and the diagnostic sensitivity was 86.3%. Both IgM and IgG classes of antibody can be detected. There is some cross-reactivity between serogroup 1 and serogroup 6 but none between serogroup 1 and serogroups 3, 4, and 5. It is suggested that CIE may provide a simple, reproducible screening test for Legionnaires' disease.