PT - JOURNAL ARTICLE AU - J A Murray AU - D N Slater AU - M A Parsons AU - M Fox AU - S Smith AU - M M Platts TI - Splenic siderosis and parenteral iron dextran in maintenance haemodialysis patients. AID - 10.1136/jcp.37.1.59 DP - 1984 Jan 01 TA - Journal of Clinical Pathology PG - 59--64 VI - 37 IP - 1 4099 - http://jcp.bmj.com/content/37/1/59.short 4100 - http://jcp.bmj.com/content/37/1/59.full SO - J Clin Pathol1984 Jan 01; 37 AB - The histological features of 40 spleens surgically removed from maintenance haemodialysis patients are reported. Twenty-four of the 40 (60%) showed massive iron loading and a significant direct correlation was found between iron loading and the amount of intravenous iron dextran administered. Since parenteral iron dextran appears to be a major factor in causing iron overload in haemodialysis patients its use as a method of iron replacement in these patients would appear inappropriate.