PT  - JOURNAL ARTICLE
AU  - Murray, J A
AU  - Slater, D N
AU  - Parsons, M A
AU  - Fox, M
AU  - Smith, S
AU  - Platts, M M
TI  - Splenic siderosis and parenteral iron dextran in maintenance haemodialysis patients.
AID  - 10.1136/jcp.37.1.59
DP  - 1984 Jan 01
TA  - Journal of Clinical Pathology
PG  - 59--64
VI  - 37
IP  - 1
4099  - http://jcp.bmj.com/content/37/1/59.short
4100  - http://jcp.bmj.com/content/37/1/59.full
SO  - J Clin Pathol1984 Jan 01; 37
AB  - The histological features of 40 spleens surgically removed from maintenance haemodialysis patients are reported. Twenty-four of the 40 (60%) showed massive iron loading and a significant direct correlation was found between iron loading and the amount of intravenous iron dextran administered. Since parenteral iron dextran appears to be a major factor in causing iron overload in haemodialysis patients its use as a method of iron replacement in these patients would appear inappropriate.