RT Journal Article
SR Electronic
T1 Splenic siderosis and parenteral iron dextran in maintenance haemodialysis patients.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 59
OP 64
DO 10.1136/jcp.37.1.59
VO 37
IS 1
A1 J A Murray
A1 D N Slater
A1 M A Parsons
A1 M Fox
A1 S Smith
A1 M M Platts
YR 1984
UL http://jcp.bmj.com/content/37/1/59.abstract
AB The histological features of 40 spleens surgically removed from maintenance haemodialysis patients are reported. Twenty-four of the 40 (60%) showed massive iron loading and a significant direct correlation was found between iron loading and the amount of intravenous iron dextran administered. Since parenteral iron dextran appears to be a major factor in causing iron overload in haemodialysis patients its use as a method of iron replacement in these patients would appear inappropriate.