TY - JOUR T1 - Physiological activation of plasminogen in full term newborn infants. JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 1264 LP - 1267 DO - 10.1136/jcp.37.11.1264 VL - 37 IS - 11 AU - M M Hilali AU - B E Gilliver Y1 - 1984/11/01 UR - http://jcp.bmj.com/content/37/11/1264.abstract N2 - Plasminogen in full term newborn infants has been measured by functional and immunological assays. Plasminogen functional activity and antigen concentration in newborn infants were about 44% and 48% of adult values respectively. Physiological activation kinetics of plasminogen in undiluted plasma at pH 7.4 and 37 degrees C using various concentrations of streptokinase and urokinase showed no significant difference in the rate of plasmin generation between plasminogen from newborn infants and adult plasminogen. These findings dispute the suggested existence of functional anomalies in plasminogen from full term newborn infants. ER -