RT Journal Article
SR Electronic
T1 Localisation of factor XIII in human tissues using an immunoperoxidase technique.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 560
OP 563
DO 10.1136/jcp.37.5.560
VO 37
IS 5
A1 J D Fear
A1 P Jackson
A1 C Gray
A1 K J Miloszewski
A1 M S Losowsky
YR 1984
UL http://jcp.bmj.com/content/37/5/560.abstract
AB An immunoperoxidase technique has been used to localise clotting factor XIII subunits A and S in human tissues. The presence of factor XIII in placenta and megakaryocytes was confirmed. Factor XIII was also found in fibroblasts, a hitherto unreported finding. Factor XIII subunits were not detected in hepatocytes, although factor XIII was found in fibroblasts in portal tracts. These findings suggest that factor XIII is not synthesised in the liver as previously thought.