TY - JOUR T1 - Immune deficiency due to adenosine deaminase and purine nucleoside phosphorylase deficiency: a simple diagnostic test. JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 1305 LP - 1307 DO - 10.1136/jcp.37.11.1305 VL - 37 IS - 11 AU - J L Maddocks AU - S A Al-Safi AU - G Wilson Y1 - 1984/11/01 UR - http://jcp.bmj.com/content/37/11/1305.abstract N2 - A simple method is described for diagnosing adenosine deaminase and purine nucleoside phosphorylase deficiency using urine. Cellulose thin layer chromatography of 1 microliter of urine from affected children was performed and deoxyadenosine and deoxyguanosine were easily detected by phosphorescence at the temperature of liquid nitrogen. This test is not expensive and can be done in any laboratory. It should be suitable for diagnostic screening in patients with immune deficiency. ER -