RT Journal Article SR Electronic T1 Immune deficiency due to adenosine deaminase and purine nucleoside phosphorylase deficiency: a simple diagnostic test. JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 1305 OP 1307 DO 10.1136/jcp.37.11.1305 VO 37 IS 11 A1 J L Maddocks A1 S A Al-Safi A1 G Wilson YR 1984 UL http://jcp.bmj.com/content/37/11/1305.abstract AB A simple method is described for diagnosing adenosine deaminase and purine nucleoside phosphorylase deficiency using urine. Cellulose thin layer chromatography of 1 microliter of urine from affected children was performed and deoxyadenosine and deoxyguanosine were easily detected by phosphorescence at the temperature of liquid nitrogen. This test is not expensive and can be done in any laboratory. It should be suitable for diagnostic screening in patients with immune deficiency.