PT  - JOURNAL ARTICLE
AU  - C S Easmon
AU  - J P Crane
TI  - Uptake of ciprofloxacin by macrophages.
AID  - 10.1136/jcp.38.4.442
DP  - 1985 Apr 01
TA  - Journal of Clinical Pathology
PG  - 442--444
VI  - 38
IP  - 4
4099  - http://jcp.bmj.com/content/38/4/442.short
4100  - http://jcp.bmj.com/content/38/4/442.full
SO  - J Clin Pathol1985 Apr 01; 38
AB  - Ciprofloxacin was concentrated within mouse peritoneal macrophages to between two and three times extracellular values. Uptake was rapid, occurred equally well with dead cells, and was not affected by lowering the pH or by prior ingestion of Staphylococcus aureus. Intracellular staphylococci were killed by extracellular concentrations of ciprofloxacin as low as 0.5 mg/l.