PT  - JOURNAL ARTICLE
AU  - J Wyatt
AU  - S R Aparicio
AU  - P Guillou
TI  - Retrospective study of histological features of acute rejection in renal allografts and comparison with circulating T cell populations.
AID  - 10.1136/jcp.38.8.858
DP  - 1985 Aug 01
TA  - Journal of Clinical Pathology
PG  - 858--863
VI  - 38
IP  - 8
4099  - http://jcp.bmj.com/content/38/8/858.short
4100  - http://jcp.bmj.com/content/38/8/858.full
SO  - J Clin Pathol1985 Aug 01; 38
AB  - The histological severity of acute rejection in renal allografts was determined for 39 rejection episodes in 30 renal transplant recipients. Data were compared with the peripheral blood T cell subset ratios measured before and at the onset of the rejection episode. T cell subset ratios showed no correlation with the histological severity of rejection, nor with the reversibility of the rejection episode. The grade of histological rejection on biopsy was predictive of graft survival. We conclude that renal biopsy remains the best method for determining the severity and outcome of acute allograft rejection episodes.