RT Journal Article
SR Electronic
T1 Retrospective study of histological features of acute rejection in renal allografts and comparison with circulating T cell populations.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 858
OP 863
DO 10.1136/jcp.38.8.858
VO 38
IS 8
A1 J Wyatt
A1 S R Aparicio
A1 P Guillou
YR 1985
UL http://jcp.bmj.com/content/38/8/858.abstract
AB The histological severity of acute rejection in renal allografts was determined for 39 rejection episodes in 30 renal transplant recipients. Data were compared with the peripheral blood T cell subset ratios measured before and at the onset of the rejection episode. T cell subset ratios showed no correlation with the histological severity of rejection, nor with the reversibility of the rejection episode. The grade of histological rejection on biopsy was predictive of graft survival. We conclude that renal biopsy remains the best method for determining the severity and outcome of acute allograft rejection episodes.