RT Journal Article
SR Electronic
T1 Discrepant toxoplasma latex agglutination test results.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 200
OP 203
DO 10.1136/jcp.42.2.200
VO 42
IS 2
A1 R E Holliman
A1 J Johnson
A1 K Duffy
A1 L New
YR 1989
UL http://jcp.bmj.com/content/42/2/200.abstract
AB The analysis of 4450 toxoplasma serology results showed that 59 (1.3%) latex agglutination reactions were not confirmed in the dye test. These discrepant results were associated with an unspecified IgM antibody but not associated with kit batch variation, inactivation of sera, concurrent cytomegalovirus infection, or the presence of hepatitis B virus "e" antigen. The latex agglutination test is useful as a screen for toxoplasma infection but false positive reactions do occur. Patients at risk of severe toxoplasmosis should be investigated by additional tests.