RT Journal Article
SR Electronic
T1 Sea-blue histiocytes and Gaucher cells in bone marrow of patients with chronic myeloid leukaemia.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 960
OP 962
DO 10.1136/jcp.41.9.960
VO 41
IS 9
A1 P R Kelsey
A1 C G Geary
YR 1988
UL http://jcp.bmj.com/content/41/9/960.abstract
AB A retrospective study of 211 bone marrow aspirates from patients with chronic myeloid leukaemia (CML) was undertaken to assess the incidence of Gaucher cells and sea-blue histiocytes. A significant correlation between the presence of these cells and prolonged survival was seen. Such storage histiocytes occurred most often during periods of relapsed chronic phase. This study shows that Gaucher cells and sea blue histiocytes are a common feature of CML and that their accumulation seems to be associated with a prolonged increase in leucocyte turnover.