PT  - JOURNAL ARTICLE
AU  - M T Brett
AU  - J T Kwan
AU  - M R Bending
TI  - Caecal perforation in a renal transplant patient with disseminated histoplasmosis.
AID  - 10.1136/jcp.41.9.992
DP  - 1988 Sep 01
TA  - Journal of Clinical Pathology
PG  - 992--995
VI  - 41
IP  - 9
4099  - http://jcp.bmj.com/content/41/9/992.short
4100  - http://jcp.bmj.com/content/41/9/992.full
SO  - J Clin Pathol1988 Sep 01; 41
AB  - A renal transplant patient developed a fatal caecal perforation after Histoplasma capsulatum infection acquired abroad. Disseminated histoplasmosis is an uncommon fungal infection, usually seen in patients with impaired immunity. The diagnosis should be considered in immunosuppressed patients who develop prolonged fever or whose health deteriorates unexpectedly after travelling overseas. The infection is endemic in parts of the United States of America but occurs all over the world. Rapid diagnosis is often possible by histological examination of infected tissues. Treatment if started early may lead to recovery, but if it is not treated it is usually fatal.