TY - JOUR T1 - Differentiation between Bernard-Soulier syndrome and immune thrombocytopenia by immunostaining of peripheral blood. JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 1296 LP - 1297 DO - 10.1136/jcp.42.12.1296 VL - 42 IS - 12 AU - L O Poulsen AU - P Johansen AU - M K Jensen AU - L Freund Y1 - 1989/12/01 UR - http://jcp.bmj.com/content/42/12/1296.abstract N2 - Peripheral blood smears from seven patients with Bernard-Soulier syndrome were examined by an immunocytochemical staining procedure using a monoclonal antibody specific for platelet glycoprotein Ib. No platelet staining was observed except for very slight staining of the large sized platelets from one of the patients. Application of the assay to blood smears from 12 patients with immune thrombocytopenia showed that their peripheral platelets stained normally, so the assay can be used to differentiate between immune thrombocytopenia and Bernard-Soulier syndrome and to confirm a diagnosis of the syndrome. ER -