TY - JOUR T1 - Observer variability in histopathological reporting of cervical biopsy specimens. JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 231 LP - 238 DO - 10.1136/jcp.42.3.231 VL - 42 IS - 3 AU - A J Robertson AU - J M Anderson AU - J S Beck AU - R A Burnett AU - S R Howatson AU - F D Lee AU - A M Lessells AU - K M McLaren AU - S M Moss AU - J G Simpson Y1 - 1989/03/01 UR - http://jcp.bmj.com/content/42/3/231.abstract N2 - Sections from 100 cervical biopsy specimens were studied by 12 consultant histopathologists to determine the robustness of the existing pathology terminology and classification. Analysis by kappa statistics showed good agreement in the diagnosis of CIN 3 and squamous carcinoma but an inability to distinguish accurately between the lesser grades of CIN. It is recommended that the classification be changed to low grade (present CIN 1 and 2) and high grade (present CIN 3) categories alone. There was very poor agreement in the identification of cellular changes associated with human papilloma virus (HPV) infection. ER -