PT - JOURNAL ARTICLE AU - A S Jack AU - I Grigor AU - C J O'Brien AU - W McMeekin AU - F Lewis AU - A M McNicol TI - Association between CAM 5.2 and anti-CD1a reactivity in lymph nodes and gastrointestinal tract epithelium. AID - 10.1136/jcp.42.3.271 DP - 1989 Mar 01 TA - Journal of Clinical Pathology PG - 271--274 VI - 42 IP - 3 4099 - http://jcp.bmj.com/content/42/3/271.short 4100 - http://jcp.bmj.com/content/42/3/271.full SO - J Clin Pathol1989 Mar 01; 42 AB - Immunocytochemical studies, using the antibodies CAM 5.2 and NA1/34 (CD1a), were performed on normal lymphoid tissue and malignant lymphomas. A population of dendritic cells in the paracortex of lymph nodes and in T cell lymphomas reacted with both antibodies. Colocalisation with antibodies was also found in gastrointestinal epithelium. Immune blotting shows that the likely basis of this reactivity is a 12 kilodalton peptide which is recognised by both antibodies. This is almost certainly the beta t peptide which has been described as the light chain of CD1a.