TY - JOUR T1 - Radiation and other pathological changes in breast tissue after conservation treatment for carcinoma. JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 152 LP - 156 DO - 10.1136/jcp.43.2.152 VL - 43 IS - 2 AU - A C Girling AU - A M Hanby AU - R R Millis Y1 - 1990/02/01 UR - http://jcp.bmj.com/content/43/2/152.abstract N2 - Histological changes in breast tissue after radiotherapy were evaluated. Changes in tissue from 17 patients previously treated for breast cancer by surgery and radiotherapy were compared with those seen in a control group treated with surgery alone. Vascular and epithelial changes were seen only in tissue from patients who had received radiotherapy and, therefore, seemed to be relatively specific; stromal changes were seen in both groups and seemed, therefore, to be non-specific. Epithelial atypia is of particular importance as it may be severe and be confused with recurrent malignancy. The presence of other changes associated with radiotherapy, particularly those in vessels, should help to avoid such misdiagnosis. ER -