RT Journal Article SR Electronic T1 Radiation and other pathological changes in breast tissue after conservation treatment for carcinoma. JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 152 OP 156 DO 10.1136/jcp.43.2.152 VO 43 IS 2 A1 A C Girling A1 A M Hanby A1 R R Millis YR 1990 UL http://jcp.bmj.com/content/43/2/152.abstract AB Histological changes in breast tissue after radiotherapy were evaluated. Changes in tissue from 17 patients previously treated for breast cancer by surgery and radiotherapy were compared with those seen in a control group treated with surgery alone. Vascular and epithelial changes were seen only in tissue from patients who had received radiotherapy and, therefore, seemed to be relatively specific; stromal changes were seen in both groups and seemed, therefore, to be non-specific. Epithelial atypia is of particular importance as it may be severe and be confused with recurrent malignancy. The presence of other changes associated with radiotherapy, particularly those in vessels, should help to avoid such misdiagnosis.