TY - JOUR T1 - Expression of 120 kilodalton protein and cytotoxicity in Helicobacter pylori. JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 733 LP - 734 DO - 10.1136/jcp.45.8.733 VL - 45 IS - 8 AU - J E Crabtree AU - N Figura AU - J D Taylor AU - M Bugnoli AU - D Armellini AU - D S Tompkins Y1 - 1992/08/01 UR - http://jcp.bmj.com/content/45/8/733.abstract N2 - Antral biopsy culture supernatants from 14 subjects with chronic gastritis, known to have IgA antibodies to the 120 kilodalton protein, showed positive recognition of this antigen in western blots against a cytotoxin positive strain of Helicobacter pylori but gave negative reactions with two cytotoxin negative strains. Control immunoblots with culture supernatants from 13 non-responders to the protein were all negative. This indicates a direct association between expression of the 120 kilodalton protein in H pylori strains and cytotoxicity. ER -