@article {Lam1011, author = {K Y Lam and S L Loke and L T Ma}, title = {Histochemistry of mucin secreting components in mucoepidermoid and adenosquamous carcinoma of the oesophagus.}, volume = {46}, number = {11}, pages = {1011--1015}, year = {1993}, doi = {10.1136/jcp.46.11.1011}, publisher = {BMJ Publishing Group}, abstract = {AIMS--To determine the direction of differentiation of the mucin secreting components in a rare group of oesophageal tumours--oesophageal squamous cell carcinomas with prominent mucin secreting components (mucoepidermoid carcinomas and adenosquamous carcinomas). METHODS--In a review of 617 cases of primary carcinoma of the oesophagus, 16 cases of squamous cell carcinoma with prominent mucin secreting components were studied using a battery of histochemical techniques. RESULTS--The mucin produced by these tumours was mixed and included a variable content of enzyme labile sialomucin (positive for mucicarmine, periodic acid Schiff, and alcian blue, and sensitive to sialidase digestion and negative for high iron diamine-alcian blue). Retrospective analysis of endoscopic biopsy specimens taken from these tumours showed that mucin was present in five (42\%) cases. CONCLUSIONS--The glandular component of this group of tumours histochemically differentiated in the direction of oesophageal glands: examination of the mucin secreting component in squamous cell carcinoma in resected specimens is therefore required for recording the true incidence of this type of tumour.}, issn = {0021-9746}, URL = {https://jcp.bmj.com/content/46/11/1011}, eprint = {https://jcp.bmj.com/content/46/11/1011.full.pdf}, journal = {Journal of Clinical Pathology} }