RT Journal Article
SR Electronic
T1 Cushing's syndrome associated with recurrent endometrioid adenocarcinoma of the ovary.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 766
OP 768
DO 10.1136/jcp.47.8.766
VO 47
IS 8
A1 S M Crawford
A1 R D Pyrah
A1 S M Ismail
YR 1994
UL http://jcp.bmj.com/content/47/8/766.abstract
AB Ectopic production of adrenocorticotrophic hormone (ACTH) by malignant neoplasms is a well recognised cause of Cushing's syndrome but is extremely rare in ovarian carcinoma. A patient who underwent surgery for ovarian carcinoma followed by a course of chemotherapy is reported. The tumour was a bilateral moderately differentiated endometrioid adenocarcinoma and contained numerous chromogranin immunoreactive endocrine cells as well as small foci of ACTH immunoreactivity. She subsequently presented with Cushing's syndrome in association with extensive pelvic recurrence of the tumour.