TY - JOUR T1 - Macroscopic assessment of pulmonary emphysema by image analysis. JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 318 LP - 322 DO - 10.1136/jcp.48.4.318 VL - 48 IS - 4 AU - P A Gevenois AU - J Zanen AU - V de Maertelaer AU - P De Vuyst AU - P Dumortier AU - J C Yernault Y1 - 1995/04/01 UR - http://jcp.bmj.com/content/48/4/318.abstract N2 - AIMS--To propose a computerised image analysis based method for measuring, on paper mounted lung sections, the area macroscopically occupied by emphysema. METHODS--The study was based on the assessment of 69 lung sections prepared following a modified Gough-Wentworth technique. The results obtained from image analysis, point counting, and panel grading methods were compared, as was the repeatability of image analysis and panel grading. RESULTS--The results from image analysis and from point counting were not significantly different (p = 0.609) and significant quadratic regressions (r = 0.96, p < 0.001) were found between measurements from image analysis and from panel grading, the computerised technique being shown to be the most reproducible. CONCLUSIONS--Image analysis is a valuable and reproducible method to measure the area of lung macroscopically involved by emphysema. ER -