RT Journal Article
SR Electronic
T1 Macroscopic assessment of pulmonary emphysema by image analysis.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 318
OP 322
DO 10.1136/jcp.48.4.318
VO 48
IS 4
A1 P A Gevenois
A1 J Zanen
A1 V de Maertelaer
A1 P De Vuyst
A1 P Dumortier
A1 J C Yernault
YR 1995
UL http://jcp.bmj.com/content/48/4/318.abstract
AB AIMS--To propose a computerised image analysis based method for measuring, on paper mounted lung sections, the area macroscopically occupied by emphysema. METHODS--The study was based on the assessment of 69 lung sections prepared following a modified Gough-Wentworth technique. The results obtained from image analysis, point counting, and panel grading methods were compared, as was the repeatability of image analysis and panel grading. RESULTS--The results from image analysis and from point counting were not significantly different (p = 0.609) and significant quadratic regressions (r = 0.96, p < 0.001) were found between measurements from image analysis and from panel grading, the computerised technique being shown to be the most reproducible. CONCLUSIONS--Image analysis is a valuable and reproducible method to measure the area of lung macroscopically involved by emphysema.