RT Journal Article
SR Electronic
T1 Malignant eccrine spiradenoma with carcinomatous and sarcomatous elements.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 871
OP 873
DO 10.1136/jcp.50.10.871
VO 50
IS 10
A1 McCluggage, W G
A1 Fon, L J
A1 O'Rourke, D
A1 Ismail, M
A1 Hill, C M
A1 Parks, T G
A1 Allen, D C
YR 1997
UL http://jcp.bmj.com/content/50/10/871.abstract
AB A case of a 60 year old man with malignant eccrine spiradenoma involving the perineum is described. Areas of typical eccrine spiradenoma were admixed with carcinomatous and sarcomatous elements. Immunohistochemical and ultrastructural analysis revealed no evidence of epithelial differentiation in the sarcomatous areas. The tumour qualified for the designation carcinosarcoma arising in eccrine spiradenoma. The clinical course was aggressive with rapid development of nodal and pulmonary metastases.