RT Journal Article
SR Electronic
T1 CD10 positive thyroid marginal zone non-Hodgkin lymphoma.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 849
OP 850
DO 10.1136/jcp.52.11.849
VO 52
IS 11
A1 E K Millar
A1 S Waldron
A1 A Spencer
A1 S Braye
YR 1999
UL http://jcp.bmj.com/content/52/11/849.abstract
AB A 72 year old woman presented with swelling of the right lobe of her thyroid gland. Fine needle aspiration and flow cytometry showed a clonal population of B cells expressing CD10 and a diagnosis of follicle centre cell lymphoma was made. Subsequent excision of the thyroid showed the typical histological features of a marginal zone non-Hodgkin lymphoma. Polymerase chain reaction showed no evidence of t (14;18). Immunohistochemistry confirmed CD10 positivity and LN1 (CDw75) expression. This is only the second report of aberrant expression of CD 10 by a marginal zone lymphoma.