RT Journal Article
SR Electronic
T1 Granulocytic sarcoma of the rectum: a rare complication of myelodysplasia.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 865
OP 866
DO 10.1136/jcp.52.11.865
VO 52
IS 11
A1 Dabbagh, V
A1 Browne, G
A1 Parapia, L A
A1 Price, J J
A1 Batman, P A
YR 1999
UL http://jcp.bmj.com/content/52/11/865.abstract
AB A 67 year old man with myelodysplasia was admitted as an emergency with a six week history of rectal bleeding and diarrhoea. Barium enema showed an irregular polypoid filling defect in the lateral wall of the proximal rectum near the rectosigmoid junction. Histology showed this to be a granulocytic sarcoma (extramedullary granulocytic leukaemia; chloroma) infiltrating the bowel. A low index of suspicion of this lesion results in an incorrect diagnosis in many such cases. A chloroacetate esterase immunoperoxidase stain will confirm the granulocytic nature of the tumour cells.