RT Journal Article SR Electronic T1 Primary large cell neuroendocrine carcinoma of the presacral region JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 880 OP 882 VO 54 IS 11 A1 P Theunissen A1 M Fickers A1 R Goei YR 2001 UL http://jcp.bmj.com/content/54/11/880.abstract AB A 7 cm diameter presacral tumour, not related to the intrapelvic organs, was found in a 51 year old woman. The needle biopsy showed a poorly differentiated large cell carcinoma. The patient died of urosepsis after chemotherapy. Postmortem examination revealed no other primary or metastatic tumour. Histological examination of the presacral tumour showed a large cell carcinoma with a trabecular pattern and strong immunoreactivity for neuroendocrine markers. The tumour was finally classified as a primary large cell neuroendocrine carcinoma of the presacral region.