RT Journal Article
SR Electronic
T1 Silicone lymphadenopathy mimicking a lymphoma in a patient with a metatarsophalangeal joint prosthesis
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 549
OP 551
DO 10.1136/jcp.53.7.549
VO 53
IS 7
A1 M Péoc'h
A1 D Duprez
A1 G Grice
A1 B Fabre-Bocquentin
A1 R Gressin
A1 B Pasquier
YR 2000
UL http://jcp.bmj.com/content/53/7/549.abstract
AB With lymph node enlargement, the possibility of a malignant process such as metastatic carcinoma or lymphoma needs to be excluded. This report describes a 47 year old woman with inguinal lymph node enlargement initially suspicious for lymphoma. Fine needle aspiration findings favoured reactive hyperplasia, but a malignant process could not be excluded. The final histological diagnosis was a foreign body granulomatous inflammatory response as a result of regionally disseminated silicone particles from an over looked metatarsophalangeal joint prosthesis. Because of the large number of joint prostheses world wide, it should be kept in mind that migration of wear particles can create granulomatous inflammation and node enlargement.