PT  - JOURNAL ARTICLE
AU  - Leake, Robin
AU  - Barnes, Diana
AU  - Pinder, Sarah
AU  - Ellis, Ian
AU  - Anderson, Liz
AU  - Anderson, Tom
AU  - Adamson, Ruth
AU  - Rhodes, Tony
AU  - Miller, Keith
AU  - Walker, Rosemary
TI  - Immunohistochemical detection of steroid receptors in breast cancer: a working protocol
AID  - 10.1136/jcp.53.8.634
DP  - 2000 Aug 01
TA  - Journal of Clinical Pathology
PG  - 634--635
VI  - 53
IP  - 8
4099  - http://jcp.bmj.com/content/53/8/634.short
4100  - http://jcp.bmj.com/content/53/8/634.full
SO  - J Clin Pathol2000 Aug 01; 53
AB  - The biochemical assay for the oestrogen receptor has shown the clinical value of knowing the concentration of the receptor within tissue. The immunohistochemical assay is rapidly taking over from the biochemical assay. Therefore, it is vital to have an equivalent scoring system that will have the same predictive value. This paper reports both a practical protocol and a scoring system that should achieve this aim. This approach should be applicable to many more biomarkers detected by immunohistochemistry.