RT Journal Article
SR Electronic
T1 Haemophagocytic syndrome and histiocytic necrotising lymphadenitis (Kikuchi's disease)
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 636
OP 638
DO 10.1136/jcp.53.8.636
VO 53
IS 8
A1 U Mahadeva
A1 T Allport
A1 B Bain
A1 W K Chan
YR 2000
UL http://jcp.bmj.com/content/53/8/636.abstract
AB A young boy presented with a rash, fever, and cervical lymphadenopathy, originally thought to be caused by tuberculosis. A lymph node biopsy showed the features of Kikuchi's disease, with necrosis and histiocytic infiltration without neutrophils. No evidence of tuberculosis was found on staining, culture, or the polymerase chain reaction. Bone marrow biopsy revealed prominent haemophagocytosis, and a diagnosis of haemophagocytic syndrome was reached. The aetiology of haemophagocytic syndrome, and its association with Kikuchi's lymphadenitis, is discussed.