RT Journal Article
SR Electronic
T1 Microorganisms in the aetiology of atherosclerosis
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 647
OP 654
DO 10.1136/jcp.53.9.647
VO 53
IS 9
A1 Morré, S A
A1 Stooker, W
A1 Lagrand, W K
A1 van den Brule, A J C
A1 Niessen, H W M
YR 2000
UL http://jcp.bmj.com/content/53/9/647.abstract
AB Recent publications have suggested that infective pathogens might play an important role in the pathogenesis of atherosclerosis. This review focuses on these microorganisms in the process of atherosclerosis. The results of in vitro studies, animal studies, tissue studies, and serological studies will be summarised, followed by an overall conclusion concerning the strength of the association of the microorganism with the pathogenesis of atherosclerosis. The role of the bacteria Chlamydia pneumoniae and Helicobacter pylori, and the viruses human immunodeficiency virus, coxsackie B virus, cytomegalovirus, Epstein-Barr virus, herpes simplex virus, and measles virus will be discussed.