RT Journal Article
SR Electronic
T1 Chronic myeloid leukaemia occurring in a patient with hairy cell leukaemia
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 940
OP 941
DO 10.1136/jcp.53.12.940
VO 53
IS 12
A1 F A Wandroo
A1 D Bareford
A1 F El-Jehani
YR 2000
UL http://jcp.bmj.com/content/53/12/940.abstract
AB Occurrences of second malignancies in hairy cell leukaemia are well recognised. Most of these malignancies are either solid tumours or lymphoproliferative disorders. The association of myeloproliferative disorders with hairy cell leukaemia (HCL) is very rare. This report describes a case of a patient with HCL who after remaining in remission developed Philadelphia chromosome positive chronic myeloid leukaemia (CML), which rapidly transformed to acute lymphoblastic leukaemia with further cytogenetic abnormalities.