RT Journal Article
SR Electronic
T1 Diagnosis of severe combined immunodeficiency
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 191
OP 195
DO 10.1136/jcp.54.3.191
VO 54
IS 3
A1 Gennery, A R
A1 Cant, A J
YR 2001
UL http://jcp.bmj.com/content/54/3/191.abstract
AB Early diagnosis of severe combined immunodeficiency (SCID) is important to enable prompt referral to a supraregional centre for bone marrow transplantation before the occurrence of end organ damage secondary to infective complications. This review outlines clinical, microbiological, and immunopathological clues that aid the diagnosis of SCID and emphasises the multidisciplinary approach needed to diagnose and treat these infants.