TY - JOUR T1 - Diagnosis of severe combined immunodeficiency JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 191 LP - 195 DO - 10.1136/jcp.54.3.191 VL - 54 IS - 3 AU - A R Gennery AU - A J Cant Y1 - 2001/03/01 UR - http://jcp.bmj.com/content/54/3/191.abstract N2 - Early diagnosis of severe combined immunodeficiency (SCID) is important to enable prompt referral to a supraregional centre for bone marrow transplantation before the occurrence of end organ damage secondary to infective complications. This review outlines clinical, microbiological, and immunopathological clues that aid the diagnosis of SCID and emphasises the multidisciplinary approach needed to diagnose and treat these infants. ER -