%0 Journal Article %A A C Deacon %A G H Elder %T ACP Best Practice No 165 %B Front line tests for the investigation of suspected porphyria %D 2001 %R 10.1136/jcp.54.7.500 %J Journal of Clinical Pathology %P 500-507 %V 54 %N 7 %X The porphyrias are uncommon disorders of haem biosynthesis and their effective management requires prompt and accurate diagnosis. This article describes methods for the determination of urinary porphobilinogen, urinary and faecal total porphyrins, and total porphyrins in erythrocytes and plasma that are suitable for use in non-specialist laboratories. The selection and interpretation of these methods, and the indications for further, more specialised, investigation are discussed. %U https://jcp.bmj.com/content/jclinpath/54/7/500.full.pdf