RT Journal Article
SR Electronic
T1 ACP Best Practice No 165
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 500
OP 507
DO 10.1136/jcp.54.7.500
VO 54
IS 7
A1 A C Deacon
A1 G H Elder
YR 2001
UL http://jcp.bmj.com/content/54/7/500.abstract
AB The porphyrias are uncommon disorders of haem biosynthesis and their effective management requires prompt and accurate diagnosis. This article describes methods for the determination of urinary porphobilinogen, urinary and faecal total porphyrins, and total porphyrins in erythrocytes and plasma that are suitable for use in non-specialist laboratories. The selection and interpretation of these methods, and the indications for further, more specialised, investigation are discussed.