RT Journal Article SR Electronic T1 Best Practice No 170 JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 261 OP 267 DO 10.1136/jcp.56.4.261 VO 56 IS 4 A1 Williams, C A1 Giannopoulos, T A1 Sherriff, E A YR 2003 UL http://jcp.bmj.com/content/56/4/261.abstract AB This review will discuss the investigation of infertility, with emphasis on laboratory testing and reference to the value of other investigations, including clinical and radiological. The role of laboratory investigations is viewed within an appropriate clinically directed pathway that includes medical, surgical, and social history together with environmental factors. Because embryology and assisted reproduction techniques are developing rapidly and produce continuous changes in everyday practice, this article gives a critical review of the plethora of tests that are currently used.