TY - JOUR T1 - Thrombin switches on RANTES synthesis in RA JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 916 LP - 916 DO - 10.1136/jcp.55.12.916 VL - 55 IS - 12 A2 - , Y1 - 2002/12/01 UR - http://jcp.bmj.com/content/55/12/916.abstract N2 - Researchers have shown for the first time that development of rheumatoid arthritis (RA) entails stimulation of synthesis of a chemokine by thrombin. They further suggest that the expression of the RANTES chemokine’s mRNA occurs by a protease activated receptor-1 (PAR-1) pathway.PAR-1 and PAR-3 were expressed in isolated … ER -