PT - JOURNAL ARTICLE AU - Baldwin, L J AU - Singh, N AU - Tiltman, A TI - Virilisation in a case of transitional cell carcinoma of the ovary AID - 10.1136/jcp.2003.010892 DP - 2004 Dec 01 TA - Journal of Clinical Pathology PG - 1331--1332 VI - 57 IP - 12 4099 - http://jcp.bmj.com/content/57/12/1331.short 4100 - http://jcp.bmj.com/content/57/12/1331.full SO - J Clin Pathol2004 Dec 01; 57 AB - A 52 year old woman presented with a five month history of emotional changes, voice changes, and of abdominal discomfort. Clinical, biochemical, and radiological examinations showed evidence of virilisation, raised testosterone, and a complex ovarian mass. Microscopy of the resection specimen showed the tumour to be a transitional cell carcinoma of the ovary with luteinisation and hyperplasia of the intervening stromal cells. This is a unique case of virilisation caused by transitional cell carcinoma of the ovary. Theories as to the origin of testosterone production in non-functioning ovarian tumours are discussed.