TY - JOUR T1 - The investigation and management of obesity JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 17 LP - 25 DO - 10.1136/jcp.56.1.17 VL - 56 IS - 1 AU - M Labib Y1 - 2003/01/01 UR - http://jcp.bmj.com/content/56/1/17.abstract N2 - Obesity is a chronic condition characterised by an excess of body fat. It is a complex disorder of appetite regulation and energy metabolism controlled by specific biological factors. In the past 10 years, great progress has been made in the scientific understanding of the pathophysiology of obesity and the interactions between genetic predisposition to weight gain and the environment. This article will review the current understanding of the pathophysiology and the approach to the investigation and management of obesity. ER -