PT  - JOURNAL ARTICLE
AU  - Wandroo, F A
AU  - Murray, J
AU  - Mutimer, D
AU  - Hubscher, S
TI  - Acute myeloid leukaemia presenting as cholestatic hepatitis
AID  - 10.1136/jcp.2003.013565
DP  - 2004 May 01
TA  - Journal of Clinical Pathology
PG  - 544--545
VI  - 57
IP  - 5
4099  - http://jcp.bmj.com/content/57/5/544.short
4100  - http://jcp.bmj.com/content/57/5/544.full
SO  - J Clin Pathol2004 May 01; 57
AB  - A 40 year old man presented with abdominal pain, jaundice, weight loss, and hepatosplenomegaly. Liver function tests revealed cholestatic jaundice and a computed tomography scan showed an enlarged liver, with a normal biliary tree. Liver biopsy showed diffuse infiltration by neutrophils, monocytoid cells, and blasts. Peripheral blood film and bone marrow were consistent with acute myeloid leukaemia. After treatment with chemotherapy using an acute myeloid leukaemia protocol (UK Medical Research Council AML-12), there was complete resolution of jaundice and the patient went into complete molecular remission.