RT Journal Article SR Electronic T1 An approach to duodenal biopsies JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 1133 OP 1150 DO 10.1136/jcp.2005.031260 VO 59 IS 11 A1 S Serra A1 P A Jani YR 2006 UL http://jcp.bmj.com/content/59/11/1133.abstract AB The introduction of endoscopy of the upper digestive tract as a routine diagnostic procedure has increased the number of duodenal biopsy specimens. Consequently, the pathologist is often asked to evaluate them. In this review, a practical approach to the evaluation of a duodenal biopsy specimen is discussed. An overview of the handling of specimens is given and the normal histology and commonly encountered diseases are discussed. Finally, a description of commonly seen infections is provided, together with an algorithmic approach for diagnosis.