PT - JOURNAL ARTICLE AU - Blandamura, Stella AU - Parenti, Anna AU - Famengo, Barbara AU - Canesso, Alessandra AU - Moschino, Paolo AU - Pasquali, Claudio AU - Pizzi, Sara AU - Guzzardo, Vincenza AU - Ninfo, Vito TI - Three cases of pancreatic serous cystadenoma and endocrine tumour AID - 10.1136/jcp.2006.036954 DP - 2007 Mar 01 TA - Journal of Clinical Pathology PG - 278--282 VI - 60 IP - 3 4099 - http://jcp.bmj.com/content/60/3/278.short 4100 - http://jcp.bmj.com/content/60/3/278.full SO - J Clin Pathol2007 Mar 01; 60 AB - Aims: To report three cases of serous cystadenoma and endocrine tumour in the same pancreas, to review the literature and to evaluate the clinicopathological features of the tumours. Cases: Three women (71, 57 and 31 years old) were admitted to hospital, two for diseases unrelated to the pancreas and the third for increasing obstructive jaundice in von Hippel-Lindau disease. Preoperative examination showed two distinct lesions in the first patient and only cystic lesions in the other two. Results: Histological examination of the pancreas showed one serous oligocystic adenoma associated with a benign, well-differentiated endocrine tumour, one serous oligocystic adenoma associated with an endocrine microadenoma, and a von Hippel-Lindau-related cystic neoplasm with a well-differentiated endocrine carcinoma. Conclusions: Serous cystadenoma associated with endocrine tumour shows some clinicopathological differences with respect to the two tumours considered separately, and with respect to von Hippel-Lindau-related cases, although there is no convincing evidence at present to justify considering this association as a separate entity.