PT  - JOURNAL ARTICLE
AU  - Katherine E Robertson
AU  - Peter D Forsyth
AU  - Paul J Batstone
AU  - David A Levison
AU  - John R Goodlad
TI  - Kikuchi’s disease displaying a t(2:16) chromosomal translocation
AID  - 10.1136/jcp.2006.038646
DP  - 2007 Apr 01
TA  - Journal of Clinical Pathology
PG  - 433--435
VI  - 60
IP  - 4
4099  - http://jcp.bmj.com/content/60/4/433.short
4100  - http://jcp.bmj.com/content/60/4/433.full
SO  - J Clin Pathol2007 Apr 01; 60
AB  - Kikuchi’s disease is a rare self-limiting lymphoproliferative condition of unknown aetiology, characterised by acute or subacute necrotising lymphadenitis. It is a benign condition that can mimic malignant lymphoma. In this report, a case of Kikuchi’s disease associated with a chromosomal abnormality is described. This is the first report in the literature of such a case and it highlights an important learning point; benign lymphoproliferative conditions can be associated with chromosomal abnormalities that are more typically associated with malignant lymphoproliferative conditions such as malignant lymphoma. The report illustrates the necessity for interpreting cytogenetic data in the relevant clinical and histopathological context in a multidisciplinary setting to avoid misdiagnosis and inappropriate treatment.