TY - JOUR T1 - Plexiform angiomyxoid myofibroblastic tumour: differential diagnosis of gastrointestinal stromal tumour in the stomach JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 1136 LP - 1137 DO - 10.1136/jcp.2008.059162 VL - 61 IS - 10 AU - T T Rau AU - A Hartmann AU - W Dietmaier AU - J Schmitz AU - W Hohenberger AU - F Hofstaedter AU - K Katenkamp Y1 - 2008/10/01 UR - http://jcp.bmj.com/content/61/10/1136.abstract N2 - Mesenchymal tumours other than gastrointestinal stromal tumours are rare in the stomach. Nevertheless it is important to incorporate them into the differential diagnosis. Plexiform angiomyxoid myofibroblastic tumour is a recently described new entity of a presumably benign mesenchymal gastric tumour. This report presents what is believed to be the third case of this tumour. The tumour is characterised by bland spindle cells in a plexiform pattern, a mucinous extracellular matrix and a network of thin blood vessels. These findings are completely in line with the two previous reported cases. There was a strong positivity for α-smooth muscle actin and a low proliferation index (<2%). The tumour had no C-KIT or CD34 expression and no mutation in the C-KIT and PDFGRα genes. Plexiform angiomyxoid myofibroblastic tumour may present a new mesenchymal tumour entity in the stomach. ER -