TY - JOUR T1 - RNA interference screening demystified JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 195 LP - 200 DO - 10.1136/jcp.2008.058735 VL - 62 IS - 3 AU - C J Lord AU - S A Martin AU - A Ashworth Y1 - 2009/03/01 UR - http://jcp.bmj.com/content/62/3/195.abstract N2 - Genetic screens, where the effects of modifying gene function on cell behaviour are assessed in a systematic fashion, have for some time provided useful information to those interested in disease pathogenesis and treatment. Genetic screens exploiting the phenomenon of RNA interference (RNAi) are now becoming commonplace. This article explains the different RNAi screen formats and describes some of the applications of RNAi screening that may be pertinent to the research pathologist. ER -