PT - JOURNAL ARTICLE AU - J M S Bartlett AU - J Starczynski AU - Neil Atkey AU - E Kay AU - A O'Grady AU - Michael Gandy AU - Merdol Ibrahim AU - Bharat Jasani AU - I O Ellis AU - S E Pinder AU - R A Walker TI - HER2 testing in the UK: recommendations for breast and gastric in-situ hybridisation methods AID - 10.1136/jcp.2011.089847 DP - 2011 Aug 01 TA - Journal of Clinical Pathology PG - 649--653 VI - 64 IP - 8 4099 - http://jcp.bmj.com/content/64/8/649.short 4100 - http://jcp.bmj.com/content/64/8/649.full SO - J Clin Pathol2011 Aug 01; 64 AB - These guidelines supplement existing guidelines on HER2 testing by immunohistochemistry and in-situ hybridisation(ISH) methods in the UK. They provide a specific focus on aspects of guidance relevant to HER2 ISH testing methods, both fluorescent and chromogenic. They are formulated to give advice on methodology, interpretation and quality control for ISH-based testing of HER2 status in common tumour types, including both breast and gastric tumours. The aim is to ensure that all ISH-based testing is accurate, reliable and timely.